A system and method causes a computer to detect and perform actions on structures identified in computer data. The system provides an analyzer server, an application program interface, a user interface and an action processor. The analyzer server receives from an application running concurrently data having recognizable structures, uses a pattern …Abstract. An intelligent automated assistant system engages with the user in an integrated, conversational manner using natural language dialog, and invokes external services when appropriate to obtain information or perform various actions. The system can be implemented using any of a number of different platforms, such as the web, email ...1. Start with a simple keyword search. Go to patents.google.com and enter the keywords in the search bar. Example query: oral care. This will returns patents …US20200054559A1. The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or in B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally …The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides …Oct 1, 2021 · A messenger ribonucleic acid (mRNA) comprising an open reading frame (ORF) that encodes at least two domains of a SARS-CoV-2 Spike protein, and less than the full length spike protein. 2. The mRNA of claim 1, wherein one of the two domains is an N-terminal domain (NTD) of a SARS-CoV-2 Spike protein. 3. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 1953-04-10 Filing date 1954-04-09 Publication date 1957-10-15 ... In a Japanese patent application (application No. 1676/50, publicized on June 5, 1950) a process was described according to which a certain strain or ergot (Claviceps ... Abstract. A spacecraft having a triangular hull with vertical electrostatic line charges on each corner that produce a horizontal electric field parallel to the sides of the hull. This field, interacting with a plane wave emitted by antennas on the side of the hull, generates a force per volume combining both lift and propulsion. Jun 4, 2021 · Formula to generate search URLs. This file: Google spreadsheet 10. Filter search results. Lastly, on the search result page, you can apply different filters on the “Patent Office”, the ... The touch screen 70 is a transparent panel that is positioned in front of the display device 68. The touch screen 70 may be integrated with the display device 68 or it may be a separate component. The touch screen 70 is configured to receive input from a user's touch and to send this information to the processor 56.Consolidated Rules – The patent rules in effect as of March 29, 2024. Subsequent Publications (After July 31, 2022) – A listing of documents that made changes to USPTO patent examining policies and procedures after July 31, 2022, and are under consideration for inclusion in a future publication of the MPEP. This listing is current as of ...Oral pharmaceutical solution comprising a pharmaceutically acceptable salt of lisdexamfetamine, and a pharmaceutically acceptable aqueous carrier comprising a buffer and a cosolvent selected from the group consisting of a glycol, a polyol, and a mixture thereof, wherein the pH of the solution is from 5.5 to 9.0. The oral pharmaceutical …2005-08-30. Method and apparatus for personalized conference and hands-free telephony using audio beaming. US11082763B2 ( en ) 2021-08-03. Handheld acoustic hailing and disruption systems and methods. US20170148466A1 ( en ) 2017-05-25. Method and system for reducing background sounds in a noisy environment.System and methods for anonymously selecting subjects for treatment against an infectious disease caused by a pathogen. The system comprises a plurality of electronic devices comprising instructions to generate an ID and, when in proximity of another such electronic device, one or both electronic devices transmit/receive the ID to/from the other electronic …About Google Patents. Overview. Search and read the full text of patents from around the world. Next: Coverage. Patents from around the world, translated. Plus technical papers …Mar 19, 2019 · The Basics of Google Patent Search. First, there’s no universal “best” way to perform a Google patent search. That said, this article will outline how we approach patent searches—which happens to be the best way to start. Note the checkbox beneath the search menu. Check that if you want to include non-patent literature in your search. When we started Google Patents almost 10 years ago, our mission was to make patents more easily accessible. Today, we're announcing the addition of 11 more …What is Google Patents. Google Patents is Google's own patent search tool. It draws on patents from more than 100 of the biggest patent offices from around the world, enabling you to search across more than 120 million documents. As such it rivals the EPO's Espacenet for coverage. Full-text patent documents are indexed from 20 of the …The lithium-ion battery of claim 37, further comprising a polymeric separator provided intermediate the positive electrode and the negative electrode. 47. The lithium-ion battery of claim 37, wherein the lithium-ion battery has a capacity between approximately 10 mAh and 1000 mAh. 48.The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at last one targeting …U.S. Patent No. 7,326,708discloses crystalline sitagliptin dihydrogenphosphate monohydrate and a process for its preparation. It also discloses that the crystalline dihydrogenphosphate salt of the present invention exhibits pharmaceutic advantages over the free base and the previously disclosed hydrochloride salt.5. Nike’s golf glasses: Up your game with a futuristic display. Source: Wojciech Kulicki/Flickr. Golf is set to get a 21st Century upgrade, thanks to Nike’s acquisition of a patent for a ...The present disclosure relates to the field of vaccines and binding molecules, as well as preparations and methods of their use in the treatment and/or prevention of disease. Described are vaccines and binding molecules, compositions containing the same, and uses thereof for treating or preventing coronavirus infections, in particular, β …One embodiment of the present subject matter includes a cushion including a case containing a filling of foam pieces, the filling made by the process of feeding a foam block into a cutting machine; cutting the foam block with the cutting machine; collecting a first plurality of foam pieces with an approximately 0.375 inch to an approximately 0.625 inch …In one particular embodiment, LAG-3 positive or LAG-3 expression positive tumor means that at least about 1%, or in the range of 1- 5% of the total number of tumor-infiltrating inflammatory cells (e.g., T cells, CD8+ T cells, CD4+ T cells, FOXP3+ cells) express LAG-3 on the cell surface.Additional advanced tip – Google Patents also includes the capability of searching non-patent literature using all the tips and tricks mentioned above. A user may simply select the “Scholar” look-alike logo to include the non-patent literature (the “Bulb” look-alike logo is to search the patent literature ).Google Patents Advanced Search. Search and read the full text of patents from around the world with Google Patents, and find prior art in our index of non-patent literature.Delivery: As used herein, “delivery” refers to the act or manner of delivering a compound, substance, entity, moiety, cargo or payload. Delivery Agent: As used herein, “delivery agent” refers to any substance which facilitates, at least in part, the in vivo delivery of a nucleic acid molecule to targeted cells.The lithium-ion battery of claim 37, further comprising a polymeric separator provided intermediate the positive electrode and the negative electrode. 47. The lithium-ion battery of claim 37, wherein the lithium-ion battery has a capacity between approximately 10 mAh and 1000 mAh. 48.Publication Publication Date Title. US6468525B1 2002-10-22 Probiotic formulation. TWI574633B 2017-03-21 Compositions comprising probiotic and prebiotic components and mineral salts, with lactoferrin. US8404228B2 2013-03-26 Food containing a probiotic and an isolated β-glucan and methods of use thereof.In one particular embodiment, LAG-3 positive or LAG-3 expression positive tumor means that at least about 1%, or in the range of 1- 5% of the total number of tumor-infiltrating inflammatory cells (e.g., T cells, CD8+ T cells, CD4+ T cells, FOXP3+ cells) express LAG-3 on the cell surface.A method for inducing cats to exercise consists of directing a beam of invisible light produced by a hand-held laser apparatus onto the floor or wall or other opaque surface in the vicinity of the cat, then moving the laser so as to cause the bright pattern of light to move in an irregular way fascinating to cats, and to any other animal with a ...T NE 555 NITE- STATES ATENT' O FICE; SETH YVHEELER, OF ALBANY, NEYV YORK. WRAPPING OR `TOILET PAPER ROLL. SPECIFICATION forming part of Letters Patent No. 459516, dated September 15, 1891, Application filed June 10. 1891.UNITED STATES PATENT OFFICE. NIKOLA TESLA, OF NEW YORK, N. Y., ASSIGNOB O F ONE-HALF TO CHARLES F. PECK, OF ENGLEWOOD, NEW JERSEY. ELECTRO-MAGN-ETIC MOTOR. SPECIFICATION forming part of Letters Patent No. 381.968, dated May-1, 1888. Application filed October 12. 1857.U.S. Patent No. 7,326,708discloses crystalline sitagliptin dihydrogenphosphate monohydrate and a process for its preparation. It also discloses that the crystalline dihydrogenphosphate salt of the present invention exhibits pharmaceutic advantages over the free base and the previously disclosed hydrochloride salt.Мы хотели бы показать здесь описание, но сайт, который вы просматриваете, этого не позволяет.Google patents database is built using patents from 17 patent offices* around the world. The database contains over 87 million patent publications including. Search Techniques. You can directly type text in the search bar. The search engine splits search strings and searches individual keywords in the search string.USD511342S1 2004-08-04 2005-11-08 High Tech Computer, Corp. Handheld electronic device. USD511347S1 2004-09-21 2005-11-08 Kabushiki Kaisha Toshiba Digital audio player. US20050255897A1 2004-04-29 2005-11-17 Samsung Electronics Co., Ltd. Double sliding-type portable communication apparatus.an assay is used to determine whether the patient has KRas G12D mutation using a sample (e.g., a biological sample or a biopsy sample (e.g., a paraffin-embedded biopsy sample) from a patient (e.g., a patient suspected of having a KRas G12D-associated cancer, a patient having one or more symptoms of a KRas G12D-associated cancer, and/or a …It is Theory of Electromagnetic Field that theoretical basis is held in this " field effect antigravity flight engine " patent application; Make a device that the electromagnetism outburst can take place, through the mode of electromagnetism outburst, to extraneous radiation or transmission electromagnetic energy; Form the acting of …A system for generating three-dimensional objects by creating a cross-sectional pattern of the object to be formed at a selected surface of a fluid medium capable of altering its physical state in response to appropriate synergistic stimulation by impinging radiation, particle bombardment or chemical reaction, successive adjacent laminae, representing …Abstract. Free Energy is a perpetual motion machine that operates indefinitely and independently without any other source of fuel, electricity, or any other renewable energy source other than gravity. Free Energy produces more energy than the amount of energy necessary to operate the machine itself. Never before has a machine …6. The controller of claim 1, wherein the input device is a button, the button being configured to activate a sharing interface for sharing recorded gameplay to a social graph of a user. 7. The controller of claim 6, wherein sharing recorded gameplay includes sharing one or more of an image or a video clip.Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2020-08-11 Filing date 2020-11-30 Publication date 2021-03-18 2020-08-11 Priority claimed from IL276648A external-priority patent/IL276648A/en 2020-08-11 Priority claimed from IL276665A external-priority patent/IL276665A/enWe would like to show you a description here but the site won’t allow us.Data provided by IFI CLAIMS Patent Services. The present disclosure relates to the fields of packaging, transportation, and storage of temperature-sensitive materials, such as biological and/or pharmaceutical products. Various aspects of such packaging, transportation, and storage are provided herein for ultra-low temperature materials useful ...USD504889S1 US29/201,636 US20163604F USD504889S US D504889 S1 USD504889 S1 US D504889S1 US 20163604 F US20163604 F US 20163604F US D504889 S USD504889 S US D504889S Authority US United States Prior art keywords electronic device view ornamental design design perspective Prior art date 2004-03-17 Legal …Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2009-12-04 Filing date 2010-12-06 Publication date 2011-12-22 2010-12-06 Application filed by UBER Inc, Uber Technologies Inc filed Critical UBER Inc 2010-12-06 Priority to US12/961,493 priority Critical patent/US20110313804A1/en The invention discloses a patent searching system, which comprises an IPC (Information Processing Center) classification searching module, an applicant searching module, an application number searching module, a patent display module and a statistic analysis module, wherein all modules are connected through a network, share out the work and cooperate with each other; and a small-sized database ... We would like to show you a description here but the site won’t allow us. Google's Patent Opportunity Submission Portal. Google will consider licensing offers for granted patents submitted through this portal. Google Patents is a search platform with 120+ million patent dataset covering in 100+ jurisdiction that makes it one of the best available patent databases. April 24, 2024 +1-202-455-5058 [email protected] 25, 2011 · Online patent tools. Locate online patent services and information. Patent Center. Single interface replacement for EFS-Web, Private PAIR and Public PAIR. Electronic Business Center; Check application status. Check patent application status with Patent Center. Fees and payment. Pay maintenance fees and learn more about filing fees and other ... Patents. We currently index full-text documents from the following patent offices: You can see the real-time number of documents that are included from each patent office by clicking on "around the world" on patents.google.com . These totals include all patents and published applications in our index, but we cannot guarantee complete coverage.What is Google Patents. Google Patents is Google's own patent search tool. It draws on patents from more than 100 of the biggest patent offices from around the … FIELD OF THE INVENTION. The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease. BACKGROUND TO THE INVENTION. 2005-08-30. Method and apparatus for personalized conference and hands-free telephony using audio beaming. US11082763B2 ( en ) 2021-08-03. Handheld acoustic hailing and disruption systems and methods. US20170148466A1 ( en ) 2017-05-25. Method and system for reducing background sounds in a noisy environment.The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast and ovarian cancer predisposing gene (BRCA1), some mutant alleles of which cause susceptibility to cancer, in particular breast and ovarian cancer. More specifically, the …Publication Publication Date Title. US465588A 1891-12-22 Toilet-paper roll. US453003A 1891-05-26 Toilet or wrapping paper. US714652A 1902-11-25 Toilet-paper. JP6657502B2 2020-03-04 Film package. US405412A 1889-06-18 Perforated paper. US459516A 1891-09-15 Wrapping or tolier paper roll.USD504889S1 US29/201,636 US20163604F USD504889S US D504889 S1 USD504889 S1 US D504889S1 US 20163604 F US20163604 F US 20163604F US D504889 S USD504889 S US D504889S Authority US United States Prior art keywords electronic device view ornamental design design perspective Prior art date 2004-03-17 Legal …The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast and ovarian cancer predisposing gene (BRCA1), some mutant alleles of which cause susceptibility to cancer, in particular breast and ovarian cancer. More specifically, the …Publication Publication Date Title. US174465A 1876-03-07 Improvement in telegraphy. Hogan 1913 The heterodyne receiving System, and notes on the recent arlington-salem tests. US388333A 1888-08-21 Telegraph-receiver. US382195A 1888-05-01 Chaeles selden.OF DAY'lUX, OlllU. ' FLYING-MACHINE. fipeciflcatiqn ofLettera Patent. .Eatented May 22, 1906. Application fi1 ad'Mai-ch 28,190- Serial No. 149.220; 1 and WILBUR Wmen'r, citizens of-the United n of Montgomery, and State of .0. States, residing in the city of Da ton, county no, have invented as eciiicat'ion; ur invention rlatesto that class …Google has long history of making patent data universally accessible and useful, starting more than 10 years ago by scanning old US patents into Google Patents. Today, Google is...Online patent tools. Locate online patent services and information. Patent Center. Single interface replacement for EFS-Web, Private PAIR and Public PAIR. Electronic Business Center; Check application status. Check patent application status with Patent Center. Fees and payment. Pay maintenance fees and learn more about filing …Using PATENTSCOPE you can search 116.1 million patent documents including 4.8 million published international patent applications (PCT). Detailed coverage …A method is provided for identifying and displaying video data of a user, either alone or together (in synchronization) with other data, such as biometric data acquired during a time that the video data was captured/received. The method includes storing biometric data separately from the video data, allowing the biometric data to be search quickly to …Jun 5, 2007 · Similar Documents. Publication Publication Date Title. USD590153S1 2009-04-14 Shoe storage box. USD549454S1 2007-08-28 Storage box. USD600940S1 2009-09-29 Disc container cover. USD529622S1 2006-10-03 Cryogenic storage box. USD598197S1 2009-08-18 Lid for a storage box. USD544762S1 2007-06-19 Food storage container. USD604157S1 2009-11-17 Container. Google Patents Advanced Search. Search and read the full text of patents from around the world with Google Patents, and find prior art in our index of non-patent literature.The present disclosure relates to the field of vaccines and binding molecules, as well as preparations and methods of their use in the treatment and/or prevention of disease. Described are vaccines and binding molecules, compositions containing the same, and uses thereof for treating or preventing coronavirus infections, in particular, β …To cite a patent in APA Style, list the name of the inventor, the year it was issued (in parentheses), the title of the patent (in italics), the patent number, the name of the issuing body, and the URL if available. Our free APA Citation Generator can help you create accurate citations quickly and easily. Inventor name, Initials. ( Year ). US20200054559A1. The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or in B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally comprising at ... The present invention is based upon the isolation and identification of a new human Ebola virus species, EboBun. EboBun was isolated from the patients suffering from hemorrhagic fever in a recent outbreak in Uganda. The isolated virus is a member of the Filoviridae family, a family of negative sense RNA viruses.January 18, 2024. ⋅. 15 min read. 88. SHARES. 4.4K. READS. Reading and understanding patents filed by Google can be challenging but this guide will help you to understand …Publication Publication Date Title. US4996044A 1991-02-26 Lipstick formulation and method. CA1333572C 1994-12-20 High gloss, high-shine lipstick. KR100654062B1 2006-12-05 Partial Make-up Cosmetic Composition of Solid Type and Water-in-oil Type. AU650760B2 1994-06-30 Coloured cosmetic sticks.The patent file contains at least one drawing executed in color. Copies of this patent with a color drawing will be provided by the Office upon request and payment of the necessary fee. FIG. 1 is a front view of a graphical user interface for a display screen or portion thereof showing our new design; and,6. The controller of claim 1, wherein the input device is a button, the button being configured to activate a sharing interface for sharing recorded gameplay to a social graph of a user. 7. The controller of claim 6, wherein sharing recorded gameplay includes sharing one or more of an image or a video clip.Experience: Google · Education: The George Washington University Law School · Location: Mountain View, California, United States · 500+ connections on LinkedIn. ... An Industry Patent and IP ...Includes an Advanced Search and Prior Art Finder. Take greater control of your Google Patents search, utilising search boxes for specific keyword or numeric …Oct 18, 2018 · Public Search Facility. The United States Patent and Trademark Office (USPTO) Public Search Facility located in Alexandria, VA provides the public access to patent and trademark information in a variety of formats including on-line, microfilm, and print. Trained staff are available to assist public users. Nov 30, 2023 · As part of this goal, Google has machine-annotated the worldwide patent corpus for scientific content and released the annotations publicly. The dataset includes billions of mentions of chemical compounds, diseases, proteins, genes, anatomy, etc, extracted from the full text, images, PDFs and translations of 130 million patents. The invention belongs to the field of nano materials and biomedicine, and relates to a vaccine, in particular to development of 2019-nCoV coronavirus nuclear recombinant nano vaccine. The invention also comprises a preparation method of the vaccine and application of the vaccine in animal experiments. The new corona vaccine contains graphene oxide, …Today, we're announcing the addition of 11 more countries to Google Patents with over 41 million new patent publications, bringing the total to over 87 million publications from 17 patent offices around the world. Starting today, you can now search for patents and applications from Japan, South Korea, the United Kingdom, Spain, France, …Nov 30, 2023 · As part of this goal, Google has machine-annotated the worldwide patent corpus for scientific content and released the annotations publicly. The dataset includes billions of mentions of chemical compounds, diseases, proteins, genes, anatomy, etc, extracted from the full text, images, PDFs and translations of 130 million patents. The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. USPTO’s new Diversity Information Platform: Advancing innovation through data-driven action. The unique online platform is free and available to anyone with an internet connection. Home page of the United States Patent and …
System and methods for anonymously selecting subjects for treatment against an infectious disease caused by a pathogen. The system comprises a plurality of electronic devices comprising instructions to generate an ID and, when in proximity of another such electronic device, one or both electronic devices transmit/receive the ID to/from the other electronic …. Namedraw
Patents. We currently index full-text documents from the following patent offices: You can see the real-time number of documents that are included from each patent office by clicking on "around the world" on patents.google.com . These totals include all patents and published applications in our index, but we cannot guarantee complete coverage. Did you know you can perform a patent search on Google? Check out this Google patent search tutorial! (FREE resources included below...) ⏬Registered USPTO pa...Provided herein is a novel method of game play and game components that in one embodiment are in the form of trading cards (10, 12, 40, 42, 44, 48, 54, 60, 64). However, the game components may take other forms, such as a board game, or the game may be played in different media, such as electronic games, video games, computer games, and …Cite a patent issued to an inventor by a legal authority. Source type. Required. Title. Required. Container title. Contributors. Required. Add person.Formula to generate search URLs. This file: Google spreadsheet 10. Filter search results. Lastly, on the search result page, you can apply different filters on the “Patent Office”, the ...Wikipedia entry for Google Patents.Google Patents is a search engine from Google that indexes patents and patent applications from the United States Patent and Trademark Office.USD504889S1 US29/201,636 US20163604F USD504889S US D504889 S1 USD504889 S1 US D504889S1 US 20163604 F US20163604 F US 20163604F US D504889 S USD504889 S US D504889S Authority US United States Prior art keywords electronic device view ornamental design design perspective Prior art date 2004-03-17 Legal …About Google Patents. Coverage. Next: Searching. Google Patents includes over 120 million patent publications from 100+ patent offices around the world, as well as many …The principle of operation of the silent subliminal presentation system is as follows: An audio signal in the upper frequency region of the audio spectrum (for example, 14,500 Hz) is modulated with the desired information. The type of modulation may be any type suitable for subliminal applications; frequency modulation (FM), phase modulation ...2. A coil composed'of contiguous or adjacent insulated conductors electrically con; nected in seriesand having a potential ditference of such value as to give to the coil as a whole, a capacity sufficient to neutralize its self-induction, as set forth. NIKOLA TESLA. ` …Apr 28, 2016 · As shown in FIG. 1, the craft 10 using an inertial mass reduction device comprises of an outer resonant cavity wall 100, an inner resonant cavity 200, and microwave emitters 300. The outer resonant cavity wall 100 and the inner resonant cavity wall 200 form a resonant cavity 150. The microwave emitters 300 create high frequency electromagnetic ... January 18, 2024. ⋅. 15 min read. 88. SHARES. 4.4K. READS. Reading and understanding patents filed by Google can be challenging but this guide will help you to understand …What is Google Patents. Google Patents is Google's own patent search tool. It draws on patents from more than 100 of the biggest patent offices from around the …US8366547B2 * 2010-12-06 2013-02-05 Ignite Game Technologies, Inc. Racing car wheel and controls for use in a multimedia interactive environment. US8641525B2 2011-06-17 2014-02-04 Ironburg Inventions Ltd. Controller for video game console.Abstract. An intelligent automated assistant system engages with the user in an integrated, conversational manner using natural language dialog, and invokes external services when appropriate to obtain information or perform various actions. The system can be implemented using any of a number of different platforms, such as the web, email ... FIELD OF THE INVENTION. The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease. BACKGROUND TO THE INVENTION. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2014-05-28 Filing date 2015-05-27 Publication date 2016-07-19 2014-10-02 Priority claimed from US14/505,478 external-priority patent/US9537811B2/en 2015-05-27 Priority to US14/723,400 priority Critical patent/US9396354B1/enApr 28, 2016 · As shown in FIG. 1, the craft 10 using an inertial mass reduction device comprises of an outer resonant cavity wall 100, an inner resonant cavity 200, and microwave emitters 300. The outer resonant cavity wall 100 and the inner resonant cavity wall 200 form a resonant cavity 150. The microwave emitters 300 create high frequency electromagnetic ... 2.1. Issued Patents. Question: What is an issued patent and what protection does it afford to the inventor? Answer: The term “patent” is derived from “letters of patents patent”; an open letter by which a sovereign entity conferred a special privilege or right on subject. The first recorded patent was granted to Filippo Brunelleschi in 1421 in Florence, Italy for an …Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 1996-12-13 Filing date 2002-04-24 Publication date 2003-07-01 ... 2002-09-05 Publication of US20020123775A1 publication Critical patent/US20020123775A1/en 2003-07-01 Application granted granted CriticalIn one particular embodiment, LAG-3 positive or LAG-3 expression positive tumor means that at least about 1%, or in the range of 1- 5% of the total number of tumor-infiltrating inflammatory cells (e.g., T cells, CD8+ T cells, CD4+ T cells, FOXP3+ cells) express LAG-3 on the cell surface..