The two Spalax galili soil populations were estimated to split ∼0.2– 0.4 Mya based on both whole genome and mitochondrial genome analyses (Fig. 2B and SI Materials and Methods). Population Genomic Divergence and Functional Enrichment. Puta-tively selected genes (PSGs) were identified by screening geno- Cancer, a disease due to uncontrolled cell proliferation is as ancient as multicellular organisms. A 255-million-years-old fossilized forerunner mammal gorgonopsian is probably the oldest evidence of cancer, to date. Cancer seems to have evolved by adapting to the microenvironment occupied by immune sentinel, modulating the cellular …Feb 17, 2022 · Background Naked mole-rats (Heterocephalus glaber, NMRs) and blind mole-rats (Spalax galili, BMRs) are representative subterranean rodents that have evolved many extraordinary traits, including hypoxia tolerance, longevity, and cancer resistance. Although multiple candidate loci responsible for these traits have been uncovered by genomic studies, many of them are limited to functional changes ... Scarica la mappa dei muscoli della spalla (a cura di Francesca Perta):https://docs.google.com/a/scienzebiomediche.it/document/d/1JnWBnd64tWYkwvVDNryU1VNYfCGV...A costly search for food in subterranean rodents resulted in various adaptations improving their foraging success under given ecological conditions. In Spalax ehrenbergi superspecies, adaptations to local ecological conditions can promote speciation, which was recently supposed to occur even in sympatry at sites where two soil types of …With a world population living longer as well as marked disparities in life expectancy, understanding the determinants of longevity is one of the priority research agendas in 21st century life sciences. To this end, the blind mole-rat (<i>Spalax leucodon</i>), a subterranean mammalian, has emerged a …Switch to new thesaurus. Noun. 1. Spalax - type genus of the Spalacidae. genus Spalax. mammal genus - a genus of mammals. family Spalacidae, Spalacidae - mole rats. mole rat - furry short-limbed tailless rodent resembling a true mole in habits and appearance; of eastern Europe and Middle East.Environmentally stressed regulation of genome-wide gene expression in Spalax and probably more generally in other organisms across life appears to …The bioenergetics of the vast majority of terrestrial mammals evolved to consuming glucose (Glc) for energy production under regular atmosphere (about 21% oxygen). However, some vertebrate species, such as aquatic turtles, seals, naked mole rat, and blind mole rat, <i>Spalax</i>, have adjusted their …Aug 12, 2011 · Interestingly, the Spalax ankyrin repeat domain 1 (Ankrd1) gene which was previously identified with an unusual 40–50 fold increase in expression during hypoxia in Spalax is found in the current study among the 10 genes with the largest estimated differences in read counts for muscle/hypoxia vs. muscle/normoxia . Welcome back to This Week in Apps, the weekly TechCrunch series that recaps the latest in mobile OS news, mobile applications and the overall app economy. The app industry continue...Mar 7, 2023 · Subterranean blind mole rat, Spalax, has developed strategies to withstand cancer by maintaining genome stability and suppressing the inflammatory response.Spalax cells undergo senescence without the acquisition of senescence-associated secretory phenotype (SASP) in its canonical form, namely, it lacks the main inflammatory mediators. 2. It doesn’t need eyes. Legion Media. When looking at it, it seems that the mole rat just closed its eyes, but there are no eyes at all, although there is a place where they might be placed. It ... Spalax (blind subterranean mole rat), is a mammal adapted to live in fluctuating oxygen levels, and can survive severe hypoxia and hypercapnia. The …La spalla è una delle articolazioni più complesse del corpo umano e per questo anche più soggetta ad infortuni e dolori. La spalla è un’articolazione capace ...Quick facts. The EUNIS species component has very limited information about this species. The main focus of the EUNIS species component is to provide relevant information about the European species protected by Directives, Conventions and Agreements. The species assessed in the European Red Lists prepared by the IUCN for …Music video by Daniela Spalla performing Volverás (Versión Acústica). © 2019 Universal Music Mexico S.A. de C.V.http://vevo.ly/QxOHshla spalla di una donna. In anatomia umana, la spalla è una regione di unione tra l’arto superiore e il torace. Al contrario dell'anca (l'analoga regione di unione dell'arto inferiore al tronco) è costituita da diverse unità giunturali. La principale funzione della spalla e di tutto l'arto superiore è quella di permettere di atteggiare la mano in diverse posizioni per poter …The lesser blind mole-rat (Nannospalax leucodon) is a species of rodent in the family Spalacidae.It is found in Albania, Bosnia and Herzegovina, Bulgaria, Greece, Hungary, North Macedonia, Romania, Serbia, Montenegro, Turkey and Ukraine.. Show More Prior to 2012, it was classified in the genus Spalax, but modern authors tend to separate this and …The blind mole rats (Spalacinae) reveal fascinating chromosomal variation, resulting from complex karyotype re-arrangements. This variation occurs between species, between populations of single species (polytypy) and within populations (polymorphism). This article reviews the current knowledge on blind mole rats' karyotypes and their variation.2. It doesn’t need eyes. Legion Media. When looking at it, it seems that the mole rat just closed its eyes, but there are no eyes at all, although there is a place where they might be placed. It ...Operation Spalax. Operation Spalax was a campaign that primarily targeted Colombian government organizations and private companies, particularly those associated with the energy and metallurgical industries. The Operation Spalax threat actors distributed commodity malware and tools using generic phishing topics related to COVID-19, …It is thought that Spalacidae (Rodentia, Mammalia) originated in Anatolia. They are widespread among Neogene-aged faunas in Anatolia and they are used as zonal fossils because of their strong evolutionary dynamics. Only one fossil species (S. odessanus, Middle Pliocene) has been identified from the genus Spalax, which has more than 14 …Daniela Spalla en el Teatro Metropólitan de la Ciudad de México, 1 de septiembre de 2019. Boletos a través del sistema Ticketmaster: https://www.ticketmaster...Dataset GBIF Backbone Taxonomy Rank SPECIES Published in Slepec ( Spalax) je rod hlodavců z čeledi slepcovitých. Zahrnuje celkem 13 druhů žijících ve východní Evropě, na Blízkém východě a v severní Africe . Jde o středně velké hlodavce podobné krtkům, kteří nemají žádné viditelné oči. Celý život žijí prakticky jen pod zemí, kde si hloubí nory se složitými systémy ... The principle and design of SPALAX-NG have been described extensively in previous publications (Cagniant et al., 2018 - a; Le Petit et al., 2015; Topin et al., 2015).The system consists of five main units, including all of the relevant equipment: the sample production is performed in three units (the sampling, purification, and concentration …Get ratings and reviews for the top 11 foundation companies in Woodburn, VA. Helping you find the best foundation companies for the job. Expert Advice On Improving Your Home All Pr...Ethic statement. This field study did not involve endangered or protected species. All procedures involving wild-caught animals were performed in a humane manner and were approved by the Institutional Animal Care and Use Committee at the University of South Bohemia and the Ministry of Education, Youth and Sports (n. 7942/2010-30).Cancer-free aging: Insights from Spalax ehrenbergi superspecies. 2018 Nov;47:18-23. doi: 10.1016/j.arr.2018.06.004. Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV), Av. Instituto Politécnico Nacional No. 2508, San Pedro Zacatenco, Gustavo A. Madero ...Space & Physics. Video. Podcasts. Opinion. Subscribe to Scientific American! Tetrapod Zoology. African Mole Rats: So Much More Than Just the Naked Mole Rat. An …Incipient sympatric speciation in blind mole rat, Spalax galili, in Israel, caused by sharp ecological divergence of abutting chalk-basalt ecologies, has been proposed previously based on mitochondrial and whole-genome nuclear DNA. Here, we present new evidence, including transcriptome, DNA editing, …Background: The development of complex responses to hypoxia has played a key role in the evolution of mammals, as inadequate response to this condition is frequently associated with cardiovascular diseases, developmental disorders, and cancers. Though numerous studies have used mice and rats in order to explore mechanisms that …The blind subterranean mole rat Spalax shows a remarkable tolerance to hypoxia, cancer-resistance and longevity. Unravelling the genomic basis of these adaptations will be important for biomedical applications. RNA-Seq gene expression data were obtained from normoxic and hypoxic Spalax and rat liver … 2. It doesn’t need eyes. Legion Media. When looking at it, it seems that the mole rat just closed its eyes, but there are no eyes at all, although there is a place where they might be placed. It ... The blind subterranean mole rat, Spalax ehrenbergi, is a model organism for hypoxia tolerance. This superspecies have adapted to severe environment by altering an array of hypoxia-mediated genes, among which an alteration in the p53 DNA binding domain (corresponding to R174K in humans) that hinders its transcriptional activity towards …Lesser blind mole-rats are burrowers and spend most of their life underground. But with surprisingly small feet and claws, they rely on their huge incisors to dig. When it’s time to excavate ...Facebook: https://www.facebook.com/fisioalfieriInstagram: https://www.instagram.com/fisio_osteopatia_alfieri/Sito: https://www.fisioalfieri.it/ Dove comprare...Aug 3, 2023 · The muroid rodent Nannospalax galili (syn. Spalax) is adapted to life in underground burrows and tolerates acute exposure to severe hypoxia. Adaptation to hypoxia is correlated with delayed onset of ageing and resistance against tumour formation. Spalax becomes five to seven times older than its relatives, the mouse and rat, without displaying signs of ageing or developing ageing-related ... Erminio Spalla (7 July 1897 – 14 August 1971) was an Italian professional heavyweight boxer, film actor and singer.. Spalla studied fine arts in Brera, when in 1910 he saw film footage of the world boxing championships and decided to become a professional boxer.He was the first Italian to win a European boxing title, which he did in 1923. He lost it in 1926 …Adipose-derived stem cells (ADSCs) are recruited by cancer cells from the adjacent tissue, and they become an integral part of the tumor microenvironment. Here, we report that ADSCs from the long-living, tumor-resistant blind mole rat, Spalax, have a low ability to migrate toward cancer cells compar …spalla f (plural spalle, diminutive spallétta) ( anatomy, cut of meat, portion of a garment) shoulder. ( cooking) chuck meat from the shoulder of a cow or other animal. (in the plural) back. back, rear. sidekick, second fiddle. ( theater, comedy) straight man, …Thomas C. Spalla, MD. Dr. Thomas C. Spalla is a dual board-certified facial plastic surgeon. He is board certified through The American Academy of Facial Plastic & Reconstructive Surgery and The American Board of Otolaryngology. He completed his training in Otolaryngology-Head & Neck Surgery at Henry Ford Hospital followed by a fellowship in ...Jun 1, 2012 · In Spalax, there was only one pronounced change due to hyperoxia, namely a 5 fold increase of Gsr in S. galili brain. Both Spalax species showed moderate (up to 3 fold) hyperoxic induction of antioxidant genes in brain, making this tissue the most responsive to hyperoxia (Table 1). N. xanthodon. Binomial name. Nannospalax xanthodon. ( Nordmann, 1840) Synonyms. Nannospalax nehringi ( Satunin, 1898) Spalax munzuri Coşkun, 2004. The Anatolian blind mole-rat or Nehring's blind mole-rat ( Nannospalax xanthodon) is a species of rodent in the family Spalacidae . It is found in Armenia, Georgia, and Turkey. The rudimentary eyes of the mole rat (Spalax ehrenbergi) are located under the skin and do not respond to light stimuli. However, removal of the eyes disturbs photoperiod perception in these animals. To help clarify the possibly remaining function of the eyes in this species, the authors studied their development and ultrastructure. Slepec ( Spalax) je rod hlodavců z čeledi slepcovitých. Zahrnuje celkem 13 druhů žijících ve východní Evropě, na Blízkém východě a v severní Africe . Jde o středně velké hlodavce podobné krtkům, kteří nemají žádné viditelné oči. Celý život žijí prakticky jen pod zemí, kde si hloubí nory se složitými systémy ... PMID: 26073269. DOI: 10.1016/j.apradiso.2015.05.019. Abstract. In the context of the verification regime of the Comprehensive nuclear Test ban Treaty (CTBT), CEA is … The rudimentary eyes of the mole rat (Spalax ehrenbergi) are located under the skin and do not respond to light stimuli. However, removal of the eyes disturbs photoperiod perception in these animals. To help clarify the possibly remaining function of the eyes in this species, the authors studied their development and ultrastructure. Cosmos (Cobra 1976; Spallax 1999). Cosmos presents a sumptuously textured Paris date recorded at Paris' Studio Hautefeuille in August 1976, drummer Larry ...la spalla di una donna. In anatomia umana, la spalla è una regione di unione tra l’arto superiore e il torace. Al contrario dell'anca (l'analoga regione di unione dell'arto inferiore al tronco) è costituita da diverse unità giunturali. La principale funzione della spalla e di tutto l'arto superiore è quella di permettere di atteggiare la mano in diverse posizioni per poter …The blind mole rat Spalax ehrenbergi is a solitary, subterranean rodent that digs and inhabits a system of branching tunnels, with no above-ground exits, which it never leaves unless forced to. To survive, the mole rat must be able to orient efficiently in its tunnel system. The sensory channels available for spatial orientation in the subterranean …PMID: 26073269. DOI: 10.1016/j.apradiso.2015.05.019. Abstract. In the context of the verification regime of the Comprehensive nuclear Test ban Treaty (CTBT), CEA is …Escucha “Puro Teatro” en tu plataforma streaming favorita: https://universalmusicmexico.lnk.to/PuroTeatro Suscríbete al canal de YouTube de Daniela Spalla: ...spalla f (plural spalle, diminutive spallétta) ( anatomy, cut of meat, portion of a garment) shoulder. ( cooking) chuck meat from the shoulder of a cow or other animal. (in the plural) back. back, rear. sidekick, second fiddle. ( theater, comedy) straight man, …Operation Spalax. Operation Spalax was a campaign that primarily targeted Colombian government organizations and private companies, particularly those associated with the energy and metallurgical industries. The Operation Spalax threat actors distributed commodity malware and tools using generic phishing topics related to COVID-19, …May 29, 2018 ... Un super esercizio per il dolore di spalla causato da periartrite e infiammazione tendinea, tanto semplice quanto utile.Spalax m. A taxonomic genus within the family Spalacidae – blind mole rats.Get ratings and reviews for the top 11 foundation companies in Woodburn, VA. Helping you find the best foundation companies for the job. Expert Advice On Improving Your Home All Pr...Aug 28, 2018 ... Monza spalla x Hamilton consegnarsi la vittoria a Lewis Hamilton a Monza capito. Prospero Papaleo Biagio Olivieri max ricciardi Nicola ...Music video by Daniela Spalla performing Veneno (Lyric Video). EMI; © 2021 Universal Music Mexico S.A. de C.V.http://vevo.ly/W917FMLa spalla è un complesso articolare caratterizzato da tanta mobilità quanta instabilità. Per questo motivo presenta un apparato legamentoso importante. In qu...Jun 1, 2012 · In Spalax, there was only one pronounced change due to hyperoxia, namely a 5 fold increase of Gsr in S. galili brain. Both Spalax species showed moderate (up to 3 fold) hyperoxic induction of antioxidant genes in brain, making this tissue the most responsive to hyperoxia (Table 1). Sep 1, 2015 · DOI: 10.1016/j.apradiso.2015.05.019 Corpus ID: 205625219; Spalax™ new generation: A sensitive and selective noble gas system for nuclear explosion monitoring. @article{lePetit2015SpalaxNG, title={Spalax{\texttrademark} new generation: A sensitive and selective noble gas system for nuclear explosion monitoring.}, author={Gilbert le Petit and Antoine Cagniant and Philippe Gross and Guilhem ... Abstract. On the social scale, the blind mole rat (BMR; Spalax ehrenbergi) is an extreme. It is exceedingly solitary, territorial, and aggressive. BMRs reside underground, in self-excavated tunnels that they rarely leave. They possess specialized sensory systems for social communication and navigation, which allow them to cope with the harsh ...Abstract. Environmental stress played a major role in the evolution of the blind mole rat superspecies Spalax ehrenbergi, affecting its adaptive evolution and ecological speciation underground. Spalax is safeguarded all of its life underground from aboveground climatic fluctuations and predators. However, it encounters multiple stresses in its ...Get ratings and reviews for the top 11 gutter guard companies in Omaha, NE. Helping you find the best gutter guard companies for the job. Expert Advice On Improving Your Home All P...Oprah Winfrey reportedly sells a painting for $150 million, a rare piece entitled "Adele Bloch-Bauer II." By clicking "TRY IT", I agree to receive newsletters and promotions from M...Background: Spalax (blind subterranean mole rat), is a mammal adapted to live in fluctuating oxygen levels, and can survive severe hypoxia and hypercapnia. The …Information architecture structures large amounts of information, such as information on the Web. Learn more about information architecture and the IA. Advertisement Imagine constr...Introduction. Understanding the link between speciation and natural selection has been a central topic in the field of evolutionary biology since Darwin (Darwin 1859).Ecological speciation is a model of speciation that occurs as a by-product of natural selection (Rundle and Nosil 2005; Schluter 2009; Schluter and Conte 2009), whereby …Space & Physics. Video. Podcasts. Opinion. Subscribe to Scientific American! Tetrapod Zoology. African Mole Rats: So Much More Than Just the Naked Mole Rat. An …Apr 1, 2018 · The SPALAX R&D unit is an order of magnitude more sensitive to metastable radioisotopes of xenon). The prototype SPALAX NG station is now underproduction by Cegelec Defense. First routine measurement will be performed by fall 2017. And further work will include the commissioning and the qualification of the prototype SPALAX NG station. How much does it really cost to vacation at Universal Studios and tour all of the Harry Potter attractions? We do the math for a family of four. By clicking "TRY IT", I agree to re...La spalla è un complesso articolare caratterizzato da tanta mobilità quanta instabilità. Per questo motivo presenta un apparato legamentoso importante. In qu...Lesser blind mole-rats are burrowers and spend most of their life underground. But with surprisingly small feet and claws, they rely on their huge incisors to dig. When it’s time to excavate ...Dear Lifehacker,I've got a great big music collection on my desktop and I want it on my laptop, too. In fact, I wouldn't mind if I could have it on my media center as well. I've ...Aug 12, 2011 · Interestingly, the Spalax ankyrin repeat domain 1 (Ankrd1) gene which was previously identified with an unusual 40–50 fold increase in expression during hypoxia in Spalax is found in the current study among the 10 genes with the largest estimated differences in read counts for muscle/hypoxia vs. muscle/normoxia . Aug 9, 2013 · Conclusions: This report provides pioneering evidence that Spalax is not only resistant to spontaneous cancer but also to experimentally induced cancer, and shows the unique ability of Spalax normal fibroblasts to inhibit growth and kill cancer cells, but not normal cells, either through direct fibroblast-cancer cell interaction or via soluble ... Sep 9, 2016 · The blind subterranean mole rat, Spalax ehrenbergi, is a model organism for hypoxia tolerance.This superspecies have adapted to severe environment by altering an array of hypoxia-mediated genes, among which an alteration in the p53 DNA binding domain (corresponding to R174K in humans) that hinders its transcriptional activity towards apoptotic genes. A Spalax KFT., a színesképes-csomagolt virághagyma forgalmazás magyarországi piacvezető cége. Az itt elérhető oldalakon megismerheti cégünket, bepillantást nyerhet a virághagyma csomagolás csúcsszintű technológiájába, tájékozódhat a forgalmazás feltételeiről, és nem utolsó sorban megismerkedhet teljes kínálatunkkal, információkat …Nov 11, 2005 · The two northern Israeli species, Spalax galili (2n = 52) and Spalax golani (2n = 54), range in cool humid climate, whereas the central species, Spalax carmeli (2n = 58), ranges in warm humid climate, and the southern species, Spalax judaei (2n = 60), ranges in warm dry climate (figures 5, 11, and 12 in ref. 7). Generally, the complex extends ... This guide ranks the best online master's programs in child and adolescent psychology. Courses like theory of personality and social psychology will prepare graduates. Written by G...Sympatric speciation is still highly controversial. Here we demonstrate, based on genome-wide divergence analysis, that sympatric speciation in the blind subterranean rodent Spalax galili encompasses multiple and widespread genomic adaptive complexes associated with the sharply divergent and abutting basalt and chalk soil populations. …Daniela Spalla - Si Te Alejas (Video Oficial) Escucha “Si Te Alejas” en tu plataforma streaming favorita:https://universalmusicmexico.lnk.to/Sitealejas Conec...How many species of spalax are there? Spalax is a genus of blind mole-rats that includes 50 subspecies. What is the range of spalax? Various …Steampunk refers to an art form that adds an antiquated Victorian aesthetic to modern technology. Learn about steampunk and steampunk technology. Advertisement Flickering gas lamps...Aug 9, 2013 · Conclusions: This report provides pioneering evidence that Spalax is not only resistant to spontaneous cancer but also to experimentally induced cancer, and shows the unique ability of Spalax normal fibroblasts to inhibit growth and kill cancer cells, but not normal cells, either through direct fibroblast-cancer cell interaction or via soluble ... Background: The development of complex responses to hypoxia has played a key role in the evolution of mammals, as inadequate response to this condition is frequently associated with cardiovascular diseases, developmental disorders, and cancers. Though numerous studies have used mice and rats in order to explore mechanisms that …
Violoncello da spalla. The violoncello da spalla, known informally as the cello da spalla, is a small cello played braced against the shoulder.. The violoncello da spalla was designed to be played by violinists, who have limited experience playing instruments such as the viola da gamba or cello, which are held in a vertical position fixed between legs.. Loire valley tours
1 INTRODUCTION. The delivery and utilization of O 2 is of great importance to the survival of many organisms. In eukaryotic organisms, O 2 oxidizes glucose to carbon dioxide and water, and generates adenosine 5′-triphosphate (ATP), which is essential for their survival and activities. 1 However, in some situations such as high-altitude and deep ocean …Daniela Spalla - Si Te Alejas (Video Oficial) Escucha “Si Te Alejas” en tu plataforma streaming favorita:https://universalmusicmexico.lnk.to/Sitealejas Conec...Hypoxic Spalax broadly downregulates genes from major liver function pathways. This energy-saving response is likely a crucial adaptation to …#DanielaSpalla #Aceleré Escucha "DARA", el nuevo álbum de Daniela Spalla, en tu plataforma preferida:https://universalmusicmexico.lnk.to/DARA Subscríbete al ...A Hamburg, New York, man was forced to give up his 11-foot, 750-pound pet alligator after local authorities determined he was keeping the reptile illegally. WKBW’s Michael Schwartz reports. If ...Erminio Spalla (7 July 1897 – 14 August 1971) was an Italian professional heavyweight boxer, film actor and singer.. Spalla studied fine arts in Brera, when in 1910 he saw film footage of the world boxing championships and decided to become a professional boxer.He was the first Italian to win a European boxing title, which he did in 1923. He lost it in 1926 …Apr 1, 2018 · The SPALAX R&D unit is an order of magnitude more sensitive to metastable radioisotopes of xenon). The prototype SPALAX NG station is now underproduction by Cegelec Defense. First routine measurement will be performed by fall 2017. And further work will include the commissioning and the qualification of the prototype SPALAX NG station. Диск колісний сталевий Vito 639 6.5J x16H2 ET60 чорний Original MB-A6394013602. Детальна інформація про товар/послугу та постачальника. Ціна та умови постачанняAdaptive methylation regulation of - PNASDataset GBIF Backbone Taxonomy Rank SPECIES ClassificationA balanced immune response is a cornerstone of healthy aging. Here, we uncover distinctive features of the long-lived blind mole-rat (Spalax spp.) adaptive immune system, relative to …Taxonomy. Previously described in 1909 by Lajos Méhel as a subspecies of the Balkan mole-rat ( S. graecus ), a 2013 morphological and phylogenetic analysis found it and the Oltenia blind mole-rat ( S. istricus) to be distinct, well-defined species. It is thought to be the sister species to S. graecus, and it is thought that the Carpathian ...Yelp is the best place to find and share your opinions on local businesses. Whether you are looking for a banquet hall, a massage therapy, or a day spa, you can read more on Yelp and discover the best options near you. Check out BabylonSpaLax, a relaxing and cozy spa in Babylon, NY, and see what other customers have to say about their services and …Space & Physics. Video. Podcasts. Opinion. Subscribe to Scientific American! Tetrapod Zoology. African Mole Rats: So Much More Than Just the Naked Mole Rat. An …Mar 22, 2016 · Spalax image by Vivan755, CC BY-SA 3.0. Subterranean rodents are not especially familiar animals to the majority of we humans, but their diversity, widespread distribution and geological longevity ... Spalax Mediterranean blind mole-rats (Also: Ukrainian blind mole-rats) Facebook. Twitter. Kingdom Animalia animals. Animalia: information (1) Animalia: pictures (22764) .
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